MK-677 (Ibutamoren): The Complete Guide – How to Use It, Key Benefits & PCT Explained
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At DiscountedSARMs.co.uk, we’re committed to providing premium-quality research compounds with full transparency and up-to-date scientific information. One of the most in-demand products in our range is MK-677 (Ibutamoren) — a potent growth hormone secretagogue that delivers real, long-term performance and recovery benefits.
In this guide, we’ll cover what MK-677 is, how to use it, its main benefits, and whether you need to run PCT after a cycle.
💡 What Is MK-677?
MK-677, also known as Ibutamoren, is an orally active growth hormone (GH) secretagogue. It works by mimicking the hunger hormone ghrelin and binding to ghrelin receptors in the brain, stimulating a natural increase in GH and IGF-1 levels — both vital for muscle growth, recovery, and fat metabolism.
Originally researched for treating muscle-wasting conditions and growth hormone deficiencies, it’s now widely used in fitness and bodybuilding communities thanks to its powerful and well-tolerated effects.
✅ MK-677 Benefits
1. Increased GH & IGF-1 Production
Daily use of MK-677 significantly raises GH and IGF-1 levels, leading to enhanced muscle-building and recovery. Clinical trials demonstrated up to a 60% increase in IGF-1 after two months at 25mg/day¹.
2. Lean Muscle Growth
Research confirms MK-677 supports lean muscle mass gain, especially in individuals undergoing resistance training or recovering from muscle loss².
3. Fat Loss & Recomposition
By boosting growth hormone naturally, MK-677 enhances fat oxidation, aiding in the reduction of stubborn visceral fat³.
4. Deep Sleep & Recovery
MK-677 improves REM and deep sleep phases, allowing users to recover faster and enjoy improved energy and performance⁴.
5. Anti-Aging & Skin Support
The increase in collagen and tissue regeneration leads to firmer skin, healthier hair, and overall rejuvenation.
6. Bone Density Improvement
Clinical studies show enhanced bone mineral density, making MK-677 a great long-term option for joint and skeletal health⁵.
📅 How to Use MK-677
Recommended Dose: 10–25 mg per day
Administration: Taken orally (no injections required)
Best Time: In the evening, ideally before bed, to optimise natural GH spikes during sleep
Cycle Length Options:
8–12 weeks for muscle growth or recomp goals
6+ months for anti-aging or therapeutic use
MK-677 has a 24-hour half-life, so once-daily dosing is sufficient. It’s ideal for beginners and experienced users alike due to its simplicity and effectiveness.
❓ Do You Need PCT After MK-677?
No – MK-677 does not require PCT.
MK-677 does not suppress testosterone production or interact with androgen receptors. It works strictly through the ghrelin pathway, stimulating your body to produce more GH and IGF-1 naturally.
If you are stacking MK-677 with other suppressive compounds like SARMs or prohormones, PCT may be needed for those compounds — but not for MK-677 itself.
🧬 Scientific References
Murphy MG et al. (1998). MK-677 increases GH/IGF-1 in humans. JCEM, 83(2), 435–441.
Chapman IM et al. (1996). Increased muscle mass in elderly adults using MK-677. JAMA, 276(21), 1906–1912.
Svensson J et al. (1998). Fat-free mass improved with MK-677. Clinical Endocrinology, 48(2), 197–202.
Copinschi G et al. (1997). MK-677 improves REM sleep in young men. Neuroendocrinology, 66(1), 54–62.
Nass R et al. (2008). Bone density gains with oral ghrelin mimetic MK-677. Ann Intern Med, 149(9), 601–611.
🛒 Ready to Buy MK-677 in the UK?
Looking for lab-tested, high-purity MK-677?
Shop with confidence at DiscountedSARMs.co.uk — your trusted UK supplier of SARMs and growth hormone secretagogues.